Faculty
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Eleni Anni, PhD Assistant Professor The focus of the current research in Dr. Anni's laboratory is on understanding how ethanol reprograms the complex genetic and epigenetic regulatory networks operating at the onset of embryonic development in Fetal Alcohol Spectrum Disorder (FASD).
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Aplin E. Aplin, PhD Professor Targeting mutant BRAF and integrin signaling in melanoma.
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Hwyda Arafat, MD, PhD Associate Professor Co-Director, Jefferson Pancreas, Biliary & Related Cancer Center My laboratory is currently investigating the molecular mechanisms involved in the regulation of oxidative stress and inflammation signaling in two pancreatic diseases, type 1 diabetes and pancreatic cancer.
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Sophie Astrof, PhD Assistant Professor The main focus of my lab is to understand cellular and molecular mechanisms of cardiovascular development in vertebrates.
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Jonathan Brody, PhD Assistant Professor Director, Surgical Research Novel therapeutic strategies for pancreatic cancer patients; primarily focused on HuR biology as it relates to the clinical management of cancer, including identifying clinically relevant HuR targets.
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Mark T. Curtis, MD, PhD Associate Professor Viral Diseases of the Central Nervous System
Demyelinating Disorders of the Central Nervous System
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Paul J. Dimuzio, MD, FACS Director, Division of Vascular and Endovascular Surgery Director, Vascular Tissue Engineering & Stem Cell Research Laboratory Program Director, Fellowship in Vascular Surgery William M. Measey Professor of Surgery Associate Professor Vascular and Endovascular Surgery, including: Carotid artery disease
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Leonard M. Eisenman, PhD Professor Structure and function of the cerebellum
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Motomi Enomoto-Iwamoto, PhD, DDS Associate Professor My research interests are to determine the regulatory mechanism of cartilage development, especially endochondral ossification and to understand pathogenesis of joint diseases such as osteoarthritis.
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Bruce A. Fenderson, PhD Professor Mechanisms of morphogenesis and malignancy; role of cell-surface carbohydrates in mediation of cell recognition during development; use of monoclonal anticarbohydrate antibodies to study lineage formation, cell differentiation, and neoplastic transformation.
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Andrzej Fertala, PhD Professor My primary research activities involve the area of extracellular matrix. In particular, my studies focus on (i) identifying pathomechanisms of heritable diseases of connective tissues caused by mutations in collagen genes, (ii) technologies to produce novel collagen-like proteins for biomedical applications, and (iii) developing novel approaches to limit excessive fibrosis.
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Theresa A. Freeman, PhD Associate Professor The areas of research focus within my laboratory can be divided into 3 main areas: Osteoarthritis, Reactive Oxygen Species (ROS) in Chondrocyte Differentiation and Cartilage Degeneration, and Non-Thermal Plasma activation of Cellular Differentiation for Tissue Regeneration
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Gerald B. Grunwald, PhD Dean, Jefferson Graduate School of Biomedical Sciences Professor, Pathology, Anatomy & Cell Biology Developmental biology and neuroscience; eye development and disease, analysis of the role of cadherin cell adhesion molecules in normal and abnormal embryonic development and in proliferative diseases of the nervous mechanisms of cadherin expression and function.
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Gyorgy Hajnoczky, MD, PhD Professor Intracellular calcium signaling; inositol trisphosphate-linked hormones; organization of calcium mobilization from endoplasmic/sarcoplasmic reticulum; mitochondrial calcium signaling; calcium-dependent control over life and death of cells; fluorometric, fluorescence microscope imaging and electrophysiological approaches.
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Noreen J. Hickok, PhD Associate Professor Development of surfaces for combating implant-associated infection; bacterial-osteoblastic cell interactions; role of extracellular bone matrix in bone formation, bacterial adhesion, and latent infections.
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Jan B. Hoek, PhD Interim Director, Cell and Developmental Biology Graduate Program Professor & Vice Chair Systems biology of intracellular signal transduction networks; deregulation of cytokine and growth factor signaling in the liver associated with chronic alcohol consumption; early signaling responses during liver regeneration; bioenergetics and mitochondrial metabolism and its role in intracellular signaling and apoptosis.
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Lorraine Iacovitti, PhD Professor Neurodegenerative Diseases, Stem Cells, Parkinson's Disease
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Renato V. Iozzo, MD Professor Director, Extracellular Matrix Program Professor of Pathology and Cell Biology, and Director of the Extracellular Matrix Program at the Kimmel Cancer Center, Thomas Jefferson University.
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Masahiro Iwamoto, DDS, PhD Associate Professor During embryogenesis, chondrocytes at the epiphyseal tip of long bone models give rise to articular tissue and persist through life, whereas chondrocytes in the shaft undergo hypertrophy, mineralization and apoptosis and are replaced by bone cells.
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Jasmin, Jean
Assistant Professor (Tenure-Track)
232 South Tenth Street
Bluemle Life Sciences Building, Rm 939
Philadelphia, PA 19107
(215) 503-9288
(215) 923-1098 fax -
Jaynes, James
Professor
1020 Locust Street
Room JAH-490
Philadelphia, PA 19107
(215) 503-4778
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Bing-Hua Jiang, PhD Professor Molecular mechanisms of PI3K, HIF-1, and VEGF signaling pathways in angiogenesis and tumorigenesis
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Suresh K. Joseph, PhD Professor Molecular mechanisms of PI3K, HIF-1, and VEGF signaling pathways in angiogenesis and tumorigenesis
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Kaji, Hideko
Professor
1020 Locust Street
Room 456A JAH
Philadelphia, PA 19107
(215) 503-6547
(215) 923-7343 fax
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Mazo, Alexander
Professor
1020 Locust Street
JAH, Rm. 485
Philadelphia, PA 19107
(215) 503-4785
(215) 923-7144 fax -
McMahon, Steven
Professor
233 South 10th Street
Suite 609
Philadelphia, PA 19107
(215) 503-9064
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A. Sue Menko, PhD Professor Role of integrins in the regulation of cell differentiation: Integrin signalling of cell differentiation events, particularly integrin-growth factor receptor coordinated signalling.
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Merry, Diane
Associate Professor
233 South 10th Street
228 BLSB
Philadelphia, PA 19107
(215) 503-4907
(215) 923-9162 fax
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Maurizio Pacifici, PhD Professor Dr. Pacificis biomedical research work focuses on mechanisms controlling skeletal development and growth in fetal and postnatal life.
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Javad Parvizi, MD, FRCS Vice Chairman, Clinical Research Professor Dr. Parvizi is a board certified orthopaedic surgeon specializing in pelvis, hip, and knee reconstruction with a special interest in hip pain in young adults and joint preservation procedures.
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Paumet, Fabienne
Assistant Professor
233 South Tenth Street
Bluemle Life Sciences Building Room 750
Philadelphia, PA 19107
(215) 503-8567
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Stephen C. Peiper, MD Peter A. Herbut Professor and Chair
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Peppel, Karsten
Associate Professor
1025 Walnut Street
Suite 311
Philadelphia, PA 19107
(215) 503-9428
(215) 503-5731 fax -
Pestell, Richard
Professor and Chairman
Director, Kimmel Cancer CenterKimmel Cancer Center
233 S. Tenth Street, Suite 1050
Philadelphia, PA 19107
(215) 503-5692
(215) 503-9334 fax -
Nancy J. Philp, PhD Associate Professor Research interest is a combination of monocarboxylate transporters; CD147; retinal pigmment epithelium; retinal metabolism; glycolysis, and JAM-C
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Radice, Glenn
Associate Professor
1025 Walnut Street
Suite 312
Philadelphia, PA 19107
(215) 503-5157
(215) 503-5731 fax -
Riobo, Natalia
Assistant Professor
233 S 10th Street
BLSB 922
Philadelphia, PA 19107
(215) 503-8549
(215) 923-1098 fax -
Makarand V. Risbud, PhD Professor Major research focus of my lab is to study the mechanisms by which nucleus pulposus cells of the intervertebral disc adapt to avascular (hypoxic) and osmotically compromising environment.
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Root, Michael
Associate Professor
233 S. 10th Street
Room 802
Philadelphia, PA 19107
(215) 503-4564
(215) 923-2117 fax -
Rostami, Abdolmohamad
Professor & Chairman, Department of Neurology
900 Walnut Street
Suite 200
Philadelphia, PA 19107
(215) 955-1234
(215) 955-1390 fax -
Rui, Hallgeir
Professor
233 South 10th Street
Suite 332
Philadelphia, PA 19107
(215) 503-9259
(215) 503-9246 fax
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Jay S. Schneider, PhD Professor Research interest is a combination of monocarboxylate transporters; CD147; retinal pigmment epithelium; retinal metabolism; glycolysis, and JAM-C
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Schwaber, James
Associate Professor
1020 Locust Street
Jefferson Alumni Hall, Suite 381
Philadelphia, PA 19107
(215) 503-7823
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Seifert, Erin
Assistant Professor
1020 Locust Street
Jefferson Alumni Hall, Suite 212D
Philadelphia, PA 19107
(215) 503-5030
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Irving M. Shapiro, BDS, PhD Gertrude and Anthony DePalma Professor, Orthopaedic Surgery Director Division, Orthopaedic Research Director, Tissue Engineering & Regenerative Medicine Training Program Mechanism of Bone Growth and Repair: Despite decades of study, the mechanism by which a thin layer of cartilage, the epiphyseal growth plate, regulates long bone growth remains poorly understood.
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Siracusa, Linda
Professor
233 South 10th Street
BLSB 719
Philadelphia, PA 19107-5541
(215) 503-4536
(215) 923-4153 fax
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Taraschi, Theodore
Professor
Vice Chair for Education1020 Locust Street
Jefferson Alumni Hall, Suite 209
Philadelphia, PA 19107
(215) 503-5020
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Uitto, Jouni
Professor & Chair
Professor of Biochemistry and Molecular Biology
Director, Jefferson Institute of Molecular Medicine233 South Tenth Street
Bluemle Life Sciences Building, Suite 450
Philadelphia, PA 19107
(215) 503-5785
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Vadigepalli, Rajanikanth
Research Assistant Professor
1020 Locust Street
Jefferson Alumni Hall, Suite 381
Philadelphia, PA 19107
(215) 955-0576
(215) 503-2636 fax -
Van Bockstaele, Elisabeth
Professor
Director, Graduate Program in Neuroscience
Farber Institute for Neurosciences900 Walnut St.
Suite 400
Philadelphia, PA 19107
(215) 503-1245
(215) 503-9238 fax
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Waldman, Scott
Professor
1025 Walnut Street
Jefferson Medical College Building, Room 901
Philadelphia, PA 19107
(215) 955-6086
(215) 955-5681 fax -
Wang, Zi-Xuan (Zoe)
Clinical Assistant Professor
125 South 11th Street
Pavillion Building, Room 207
Philadelphia, PA 19107
(215) 955-0611
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Wedegaertner, Philip
Professor
233 S. 10th St.
839 BLSB
Philadelphia, PA 19107
(215) 503-3137
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Winter, Edward
Professor
233 South 10th Street
228 BLSB
Philadelphia, PA 19107
(215) 503-4139
(215) 503-9162 fax
Current Events
On Tuesday February 26 Thomas Jefferson held its 5th Annual Scholarship Dinner ...
CDB Candidate Interviews 2013 ...
CDB Program Announces Interim Director Dr. Jan Hoek ...
Congratulations to Dr. Renato Iozzo for being appointed as Editor-In-Cheif of Matrix Biology
