James S. Harrop, MD, FACS
Professor, Department of Neurosurgery
Division Chief, Spine and Peripheral Nerve Surgery
Professor, Department of Neurosurgery
Division Chief, Spine and Peripheral Nerve Surgery
Research and Clinical Interests
Spinal cord Injury, Spinal Tumors, Degenerative spine conditions
My research focuses on... Improving the neurologic status of patients after spinal cord injuries. Several years ago there was the belief that patients with spinal cord injuries had no potential to improve neurologically. Over the last several decades through a better understanding of the pathophysiology of spinal cord injury and the nervous system patients outcomes have improved. Presently through early decompression and reconstruction of a patient's spinal column, we are seeing continued and progressively better neurologic recoveries. However, we still have a long way further to improve. The uses of translational strategies such as anti-apoptotic agents are showing future promise. These advances are aimed for not only individuals affected with trauma induced spinal conditions, but also for the treatment of spinal tumors and degenerative conditions.
The techniques that I use in my research are translation research with scientists utilizing molecular and stem cell therapy to aid in the repair of spinal cord injuries. In addition to clinical research techniques with prospective and retrospective studies.
I hope that my findings will be used to improve the quality of lives for individuals affected with spine and spinal cord disorders.
Publications
- The safety and efficacy of stem cell therapy for diabetic peripheral neuropathy in animal studies: A systematic review and meta-analysis
- The economic burden of diabetes in spinal fusion surgery: a systematic review and meta-analysis
- Patients May Return to Work Sooner After Laminoplasty: Occupational Outcomes of the Cervical Spondylotic Myelopathy Surgical Trial
- Human studies of the efficacy and safety of stem cells in the treatment of diabetic peripheral neuropathy: a systematic review and meta-analysis
- What is the True Cost of Motion Preservation? A Time-Driven Activity-Based Cost Analysis of Anterior Cervical Discectomy and Fusion versus Disc Replacement