Steven E. McKenzie, MD, PhD
Leandro M. Tocantins, MD - Farid I. Haurani, MD Director, Cardeza Foundation for Hematologic Research
Director, Hereditary Anemias Program
Associate Director, Hemophilia Center
Professor, Department of Medicine
![McKenzie, Steven E.](/content/academic/academics/colleges-schools-institutes/life-sciences/faculty-staff/faculty/mckenzie/_jcr_content/profile/image.img.jpg)
Contact
Research Office
1020 Locust Street
Suite 394
Philadelphia, PA 19107
215-955-8544
215-955-9170 fax
Featured Links
Steven E. McKenzie, MD, PhD
Leandro M. Tocantins, MD - Farid I. Haurani, MD Director, Cardeza Foundation for Hematologic Research
Director, Hereditary Anemias Program
Associate Director, Hemophilia Center
Professor, Department of Medicine
Research & Clinical Interests
Dr. McKenzie directs two major research projects. The first project involves vascular biology, with a focus on immune-mediated thrombocytopenia and thrombosis syndromes. This work, done in collaboration with Dr. Michael Reilly, led to the first model of heparin-induced thrombocytopenia and thrombosis. New work on effects of elevated cholesterol and athrosclerosis on HITT, and on microparticles and tissue factor, is ongoing.
Publications
- A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity
- Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential
- Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology
- Aspirin pharmacokinetics and pharmacodynamics through gestation
- The Function of ASK1 in Sepsis and Stress-Induced Disorders