Pawan Sharma, PhD

Aberrant cellular signaling as a result of repeated allergen exposure can promote airway smooth muscle dysfunction as observed in asthma. The major focus of our research is to identify novel cellular and molecular mechanisms by which various airway cell functions and homeostasis is maintained. Thus, we aim on discovering and identifying novel cellular mechanisms that are altered in disease state and will characterize them to develop these targets as a potential therapy in future. Overall, our research program on asthma pathogenesis uses in vitro and animal disease models that integrates translational research with a focus on real world unmet clinical needs.