Satish C. Rattan, DVM
Professor of Medicine
Research Faculty
Contact
1025 Walnut Street
College Building, Room 320
Philadelphia, PA 19107
215-955-5614
215-955-5553 fax
Satish C. Rattan, DVM
Professor of Medicine
Research Faculty
Education
Medical School
DVM, Punjab Agricultural University, Hissar, India - 1968
MS, Pharmacology, University of Houston, TX - 1970
Fellowship
Baylor College of Medicine, Houston, TX
University of Texas, South Western Medical School, Dallas, TX
Publications
- Role of mechanoregulation in mast cell-mediated immune inflammation of the smooth muscle in the pathophysiology of esophageal motility disorders
- Mendelian Randomization Analysis Reveals a Complex Genetic Interplay among Atopic Dermatitis, Asthma, and Gastroesophageal Reflux Disease
- Treatment of Severe Swallowing Dysfunction in Systemic Sclerosis with IVIG: Role of Antimuscarinic Antibodies
- In the memory of our following colleagues, and friends
- Evidence for the presence and release of BDNF in the neuronal and non-neuronal structures of the internal anal sphincter
Positions
Professor, Medicine, Thomas Jefferson Univ., Philadelphia, PA, 1989- present
Associate Professor, Harvard Medical School, Boston, MA, 1988-89
Assistant Professor, Harvard Medical School, Boston, MA, 1981-87
Assistant Professor, University of Texas Health Science Center, San Antonio, TX, 1978-81
Honors & Awards
Council of Indian Organizations Award for Professional & Academic Excellence, 2006
Janssen Award, for Basic Research in Gastroenterology, 1997
Merit Scholarship, Punjab Agricultural University, Hissar, India, 1964-68
Editorial Board
Journal of Pharmacology & Experimental Therapeutics, 1992-99
American Journal of Physiology, 2010-
American Journal of Physiology, 1992-98
Associate Editor GASTROENTEROLOGY, 1986-89
Other Experience & Professional Experience
Teaching Physiology/Pharmacology to Medical Students, 1978-2002
Chief Org. and Director of Am. Motility Society Meeting, Philadelphia, PA, 1998
Member Appointments and Promotions Committee, Thomas Jefferson University, 2000-present
Member Inst. Animal Care & Use Committee, Thomas Jefferson University, 2004-2008
Member, NIH Study Section, 2003
Member, NIH Study Section, 2013
Member, NIH Study Ssection, 2016
Expertise & Research Interests
Dr. Rattan is internationally recognized as an outstanding educator and researcher. He is frequently invited as a visiting Professor. Dr. Rattan has received multiple National and International awards in research and teaching.
In 1997, he received a prestigious Janssen Award for his outstanding basic research in Gastroenterology.
In 2006, he was honored by the Council of Indian Organizations as an outstanding professional.
Dr. Rattan's research has been continuously funded by the National Institutes of Health.
He has been an Associate Editor of GASTROENTEROLOGY, on editorial board of, and a reviewer for a number of prestigious journals.
Research Interest: Disorders of the internal anal sphincter (IAS) underlie many clinical abnormalities, such as fecal incontinence and constipation, hemorrhoids and anal fissures. Such disorders are of particular importance in the growing population of the elderly. The focus of Dr. Rattan's research has been on: 1. the nature and role of inhibitory neurotransmitters and mediators; 2. the neural pathways in the rectoanal inhibitory reflex; and 3. the molecular bases underlying myogenic tone in the IAS. Using IAS as the model of tonic smooth muscles, Dr. Rattan's basic studies have provided major advances in the field of molecular biology of the tonic versus phasic smooth muscles. The concepts learnt from his studies have direct implications in the molecular mechanisms underlying pathophysiology, and in the targeted therapeutic development in the gastrointestinal motility disorders, and in a number of other organ systems.