Yuri K. Sykulev, MD, PhD
Professor
Contact
233 South Tenth Street
Bluemle Life Sciences Building, Room 706
Philadelphia, PA 19107
215-503-4530
215-923-4153 fax
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Yuri K. Sykulev, MD, PhD
Professor
Education
Medical School
MD, MS, Pyrogov Medical Institute, Moscow, Russia, (1971-1977)
PhD, Pyrogov Medical Institute, Moscow, Russia, (1977-1982)
Fellowship
Department of Experimental and Theoretical Physics, Pyrogov Moscow Medical Institute
International Fogerty Fellow, University of Virginia, Department of Biochemistry, VA
M.I.T., Cambridge, MA
Most Recent Peer-Reviewed Publications
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs
- The DISC1–Girdin complex – a missing link in signaling to the T cell cytoskeleton
- Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides
Expertise & Research Interests
Immunobiology of cytolytic effectors and their anti-virus and anti-cancer activities.