Medical School
Temple University School of Medicine
Residency
Mount Sinai Medical Center
Fellowship
UCLA Medical Center
Michael R. Sperling, MD
Vice Chair, Neurology Research
Division Chief for Epilepsy
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory
Associate Director, Epilepsy & Clinical Neurophysiology Fellowship Programs
Baldwin Keyes Professor of Neurology
Contact Information
901 Walnut Street
Suite 400
Philadelphia, PA 19107
215-955-1222
215-955-0606 fax
Vice Chair, Neurology Research
Division Chief for Epilepsy
Director, Jefferson Comprehensive Epilepsy Center
Director, Clinical Neurophysiology Laboratory
Associate Director, Epilepsy & Clinical Neurophysiology Fellowship Programs
Baldwin Keyes Professor of Neurology
Education
Publications
- Seizure freedom and reducing the risk of sudden unexpected death in patients with focal epilepsy treated with cenobamate or other antiseizure medications
- Study-phase reinstatement predicts subsequent recall
- Left parietal structural connectivity mediates typical and atypical language laterality in temporal lobe epilepsy
- Factors influencing seizure induction in patients with intracranial EEG recording
- Real-world use of cenobamate in adults: Efficacy and predictors of treatment response
Board Certifications
- American Board of Psychiatry and Neurology
- American Board of Clinical Neurophysiology
- American Board of Psychiatry and Neurology, Epilepsy
Research & Clinical Interests
- Surgical treatment of epilepsy: outcome after surgery, predictors of surgical outcome, neurobehavioral effects of surgery;
- Mortality in epilepsy: research examining features associated with increased mortality in patients with epilepsy;
- Electrophysiology of epilepsy: studies of EEG in epilepsy, intracranial EEG in epilepsy examining features related to seizure control, seizure propagation and spread;
- Genetics of epilepsy: project examining genetic factors predisposing to heightened susceptibility for epilepsy;
- Electrophysiology of cognition;
- Investigational therapeutics in epilepsy: participation in multiple studies of new pharmaceuticals and devices to treat epilepsy.
PROFESSIONAL ACTIVITIES
- Member, Executive Committee, International League Against Epilepsy
- Chair, Publication Council, International League Against Epilepsy
- Member, Finance Committee, International League Against Epilepsy
- Member, American Epilepsy Society Investigators Workshop Committee
- Fellow, American Epilepsy Society
- Fellow, American Academic of Neurology
- Member, American Clinical Neurophysiology Society; past president
- Member, Philadelphia Neurological Society; past president
- Member, American Epilepsy Society Guideline Panel
- Board member, Epilepsy Foundation of Eastern Pennsylvania
- Chair, Epilepsy section in annual Controversies in Neurology Congress
- Organizer: Annual International Conference on Artificial Intelligence in Epilepsy and Neurological Diseases
- Organizer and lecturer at national and international Neurology and Epilepsy meetings
- Former Editor-in-Chief, Epilepsia (the journal of the International League Against Epilepsy)
Educational Activities
- Teaching medical students, residents and fellows.
- Regular instructor at resident and fellow epilepsy/neurophysiology conferences.
- Regular instructor at resident neurology conference.
Clinical Activities
- Developed Epilepsy Program at the Graduate Hospital, including design and development of the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), contributing to development of experimental antiepileptic drug program, and clinical research program.
- Developed the Comprehensive Epilepsy Center at Thomas Jefferson University, including designing and developing the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), experimental antiepileptic drug program, and clinical research program.
- Developed Intraoperative Brain Mapping Program at Thomas Jefferson University Hospital
Editorial Positions
- Editor-in-Chief, Epilepsia, 2014 – 2024
- Associate Editor: Epilepsia 2007 - 2014
- Epilepsy Research, 1999-2007
- Epilepsy Advances, 1993-95, 1996-1998
- Member - Editorial Board: Journal of Epilepsy, 1991-1999
- Reviewer: Electroencephalography and Clinical Neurophysiology, Annals of Neurology, Neurology, Epilepsia, Journal of Clinical Neurophysiology, Neuroradiology, Journal of Neurological Sciences, Archives of Neurology, JAMA, New England Journal of Medicine, Lancet