Design and testing of novel recombinant proteins with immunotherapeutic potential to treat solid tumors and metastasis.
Carmella Romeo Smith, PhD
Research Instructor
Contact Information
Research Instructor
Research & Clinical Interests
Education
Education
PhD, Thomas Jefferson University, Philadelphia PA - 2017
Fellowship
Postdoctoral Fellow, Thomas Jefferson University, Philadelphia PA
Most Recent Peer-Reviewed Publications
- Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors
- CRISPR knockout of the HuR gene causes a xenograft lethal phenotype
- HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells
- HuR posttranscriptionally regulates WEE1: Implications for the DNA damage response in pancreatic cancer cells
- HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer
Focus
immunotherapy, melanoma, recombinant proteins, protein engineering