PhD, Genomics & Computational Biology, Perelman School of Medicine, University of Pennsylvania, PA - 2023
Yang Xu, PhD
Assistant Professor
Assistant Professor
Education
Publications
- Xu Y*, Zhang S*, Lin S, Guo Y, Deng W, Zhang Y, Xue Y. WERAM: a database of writers, erasers and readers of histone acetylation and methylation in eukaryotes. Nucleic Acids Res. 2017 Jan 4; 45(D1):D264-D270.
- TEQUILA-seq: a versatile and low-cost method for targeted long-read RNA sequencing
- IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
- ESPRESSO: Robust discovery and quantification of transcript isoforms from error-prone long-read RNAseq data
- Longitudinal Large-Scale Semiquantitative Proteomic Data Stability across Multiple Instrument Platforms
- IUUCD 2.0: An update with rich annotations for ubiquitin and ubiquitin-like conjugations
Research & Clinical Interests
My primary research interests include cancer and disease transcriptome profiling, identification of signature transcripts and pathways as therapeutic targets, multi-omics data integration, and computational tool development. My recent work focuses on developing computational tools for target identification in cancer immunotherapy (TCR-T & CAR-T).