Past K30 Conferences

Date

Conference

Speaker

Title

Thursday, May 30, 2024 Gruber Lecture Björn C. Knollmann, MD, PhD
William Stokes Professor of Medicine and Pharmacology
Fellowship Director, Division of Clinical Pharmacology
Director, Vanderbilt Center for Arrhythmia Research and Therapeutics (VanCART)
Quest for Better Antiarrhythmic Drugs: Discovering New Tricks from Old Drugs
Tuesday, May 21, 2024 Ethics Conference Samantha Thomas and Soni Viren Ethical Considerations for Precision Medicine
Tuesday, May 14 2024 Departmental Research Seminars Menoosh Torkzaban GCC-directed CAR T cell therapy in metastatic colorectal cancer
Tuesday, May 7, 2024 Seminars in Human Investigation

Larry Harshyne, PhD
Department of Microbiology & Immunology
Assistant Provost for Research Conduct and Compliance
Thomas Jefferson University

Responsible Conduct of Research: Best Practices at Jefferson
Tuesday, April 16, 2024 Journal Club Victor Amajor Derivation and Validation of Novel Phenotypes of Multiple Organ Dysfunction Syndrome in Critically Ill Children
Tuesday, April 9, 2024 Ethics Conference Genevieve Lewis and Jean-Bernard Lubin Microbe-based therapeutics: ethical considerations in clinical settings
Tuesday, April 2, 2024 Seminars in Human Investigation  Jacob Elmer
Dicciani Associate Professor
Assistant Chair of Graduate Studies
Chemical & Biological Engineering
Villanova University
Overcoming Host Cell Defenses against Gene Therapy
Tuesday, March 19, 2024 Departmental Research Seminars

Kevin Lam

Dose Optimization of Azithromycin for Preterm Premature Rupture of the Membranes
Tuesday, March 12, 2024 Seminars in Human Investigation  Danny Welch Functions of the forgotten genome: Mitochondrial SNP impact cancer metastasis, immune polarization, and the microbiota
Tuesday, March 5, 2024 Journal Club Viren Soni Analytical Method Development of Drug Substances and Their Clinical Applications
Tuesday, February 20, 2024 Ethics Conference Adam Marc and Carrie Andrews

Use of Historical Controls in Clinical Research

Tuesday, February 13, 2024 Departmental Research Seminars

Erik Blomain
Department of Radiation Oncology
Thomas Jefferson University

Evolutionary pressures shape development and radiotherapy response in lung cancer and sarcoma
Tuesday, February 6, 2024 Seminars in Human Investigation (ZOOM ONLY) Ayyappa Chaturvedula

Applications of pharmacometrics in drug development and patient care

Tuesday, January 23, 2024 Departmental Research Seminars Ibram Mikhail  Morphine Pharmacokinetics in Hypodermically Cooled Patients
Tuesday, January 16, 2024 Ethics Conference (ZOOM ONLY) David Jaffe and Terry Dang Ethical Issues Regarding the Use of Human Organs or Tissue in Research
Tuesday, January 9, 2024 Seminars in Human Investigation Michael Verzi, PhD Parallels between tissue regeneration and colon cancer
2023      
Tuesday, December 19, 2023 Journal Club Adeline Yang Advances in Molecularly Targeted Therapy for Thyroid Cancer
Tuesday, December 12, 2023 Ethics Conference  Yanki Yarma and Mehnoosh Torkzaban  Ethics in biobanking
Tuesday, December 5, 2023 Seminars in Human Investigation Jason Moore Clinical Pharmacology in Early Drug Development
Tuesday, November 14, 2023 Journal Club Chazmyn Riley Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anemia in Tanzania
Tuesday, November 7, 2023 Seminars in Human Investigation David Olsen, PhD  An Academic Pharma Antimalarial Drug Discovery Collaboration:  From a Screening Hit to Advance Leads used to Decipher Malaria Biology
Tuesday, October 17, 2023 Ethics Conference     Phuong Le and Victor Amajor  The Use of AI in Medical Research
Tuesday, October 10, 2023 Journal Club Jean-Bernard Lubin  The Combined Escherichia coli Nissle 1917 and Tryptophan Treatment Modulates Immune and Metabolome Responses to Human Rotavirus Infection in a Human Infant Fecal Microbiota-Transplanted Malnourished Gnotobiotic Pig Model
Tuesday, September 19, 2023 Journal Club Mehnoosh Torkzaban  GD2-CART01 for relapsed or refractory high-risk neuroblastoma
Tuesday, September 5, 2023 Seminars in Human Investigation Brent Chamberlain  Associate Director of Cell and Gene Therapies at the Jefferson Institute for Bioprocessing (JIB).  Critical Considerations for Improved Cryopreservation of Cell Therapies
May 23, 2023 Ethics Conference Nicole Wolfset The ethical considerations of using a pediatric hematopoietic stem cell donor
May 16, 2023 Departmental Research Seminar Molly Halloran The Role of STAT3 Gain of Function Mutations in Large Granular Lymphocytic Leukemia
May 11, 2023 19th Annual Charles M. Gruber Lecture Alexander A. Vinks, PhD, PharmD, FCP, Cincinnati Children’s Research Foundation Endowed Chair, Professor of Pediatrics & Pharmacology, University of Cincinnati, College of Medicine Model Informed Precision Dosing: The Clinical Pharmacologyof Goldilocks
May 9, 2023 Seminars in Human Investigation Gabe Romano, PhD Chemokine-based approaches to treat immunologically “cold” tumors
April 18, 2023 Departmental Research Seminar Gideon Stitt Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial
April 4, 2023 Seminars in Human Investigation Chang Li, PhD  In vivo precision genome engineering in HSCs for hemoglobinopathies
March 21, 2023 Departmental Research Seminar Ibram Mikhail Intravenous Morphine Pharmacokinetics in Hypothermic Cooling
March 14, 2023 Journal Club Kevin Lam Evaluation of FDA Drug Label Recommendations for Coadministration of Antivirals and Acid-Reducing 
March 7, 2023 Seminars in Human Investigation Damien Thevenin, PhD  Targeting Cancer Cells with pH-responsive Transmembrane Peptides
February 21, 2023 Ethics Conference Zachary Urdang Ethical utilization of machine learning technology in patient care and research
February 7, 2023  Seminars in Human Investigation Matt Rizk, PhD Clinical pharmacology and dose selection of the COVID therapeutic molnupiravir
January 24, 2023 Departmental Research Seminar Lindsay Weil  GUCY2C as a Target for CAR-T Cells to Treat Pancreatic Cancer
January 17, 2023 Ethics Conference Signe Caksa and Molly Halloran  Ethical Considerations for Phase 1 Trials in Oncology
2022      
December 20, 2022 Journal Club Gideon Stitt Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
December 6, 2022 Seminars in Human Investigation Aaron R Haeusler, PhD Pathways to ALS interventions
November 22, 2022 Departmental Research Seminar Zachary Urdang

Unsupervised Discovery of Medications Associated with Favorable Acoustic Neuroma Outcomes

November 15, 2022 Journal Club Shaik Rashid Increased pro-BNP in hematopoietic stem cell donors who receive G-CSF
November 8, 2022 Seminars in Human Investigation Kevin Downes, MD Optimizing Vancomycin Therapy in Children
October 18, 2022 Ethics Conference Rachel Cain and Ibram Mikhail  Ethical Issues in Research Involving Participants With Opioid Use Disorder
October 11, 2022 Journal Club Molly Halloran  Risk of Malignancy with Genetically Modified T Cells? A Review of Long-term Follow-up for the Development of Subsequent Malignancies in Patients Treated with Genetically Modified IECs
October 4, 2022 Seminars in Human Investigation Abhik Das, PhD RTI International  Clinical trials in Neonatology: Design and analyses issues
September 13, 2022 Ethics Conference Tyler Alexander and Gideon Stitt Vaccine approval and testing – weighing ethical considerations
June 21, 2022 Journal Club Gideon Stitt Early Discontinuation, Results Reporting, and Publication of Pediatric Clinical Trials
June 14, 2022 Departmental Research Seminars Madison Crutcher GUCY2C as a Target for CAR-T Cells to Treat Pancreatic Cancer
June 7, 2022 Seminars in Human Investigation Tomoyuki Mizuno, PhD Physiologic based pharmacokinetic modeling as a tool for predicting drug behavior in pediatrics: Buprenorphine in neonates and other examples
May 31, 2022 Seminars in Human Investigation John Mondick, PhD Cipaglucosidase Alfa/Miglustat Enzyme Replacement Therapy for the Treatment of Infantile and Late Onset Pompe Disease: Developing the Appropriate Model for the Question”
May 24, 2022 Ethics Conference Zachary Urdang IRB for First Nations, data sovereignty, data sharing, and big-data
May 17, 2022 Departmental Research Seminars Alison O'Neill Characterizing a Novel Preclinical Model for Targeted Drug Development in Papillary Thyroid Cancer
April 19, 2022 Ethics Conference Reena Ghosh Exploring the Ethics of Digital Health and Wearables Research
April 12, 2022 Seminars in Human Investigation Babar Bashir, MD Scientific & Therapeutic Potential of Phase I Trials – The evolution in oncology drug development
March 22, 2022 Departmental Research Seminars Ida Micaily Chordoma: A Clinicopathologic Correlation
March 15, 2022 Journal Club Shaik Rashid Daprodustat for treatment of Anemia in patients with CKD and ESRD: Analysis of ASCEND-ND and ASCEND-D Trials
March 8, 2022 Seminars in Human Investigation Kevin Downes, MD Challenges to Personalized Antimicrobial Dosing in Pediatrics: How Microsampling Can Help Us Move from Therapeutic Drug Monitoring to Management
February 22, 2022 Ethics Conference Haani Jafri & Madison Crutcher AmazonCare: Healthcare in the Palm of your Hand
February 15, 2022 Departmental Research Seminars Ibram Mikhail Morphine Pharmacokinetics in Critically-Ill Pediatric Patients Through One Compartment Models
February 8, 2022 Seminars in Human Investigation Mara Becker, MD The serendipitous journey to PROMOTE individualized therapy in JIA
January 18, 2022 Departmental Research Seminars Ranju Kunwor Two step approach to allogeneic hematopoietic stem cell transplant in myelodysplastic syndrome patients
January 25, 2022 Ethics Conference Selin Isguven & Gideon Stitt We Can’t Fix What We Don’t Measure: a Discussion on the Choice of Research Goals and Endpoints
2021      
December 21, 2021 Journal Club Zachary Urdang Adjuvants in cancer immunotherapy
December 14, 2021 Ethics Conference Colleen Isabelle & Alison O'Neill Ethics of Activism in Clinical Research
December 7, 2021 Seminars in Human Investigation Sara L. Van Driest, MD, PhD. Using Real World, Electronic Health Records Data for Precision Medicine Research
November 23, 2021 Departmental Research Seminars Shaik Rashid FOLFIRINOX vs Gem-Abraxane in advanced stage pancreatic cancer
November 16, 2021 Journal Club Ida Micaily “Osimertinib in EGFR mutated NSCLC”
November 9, 2021 Seminars in Human Investigation Patricia (Pat) Pioli, Ph.D., Associate Professor Dept of Microbiology and Immunology Geisel School of Medicine at Dartmouth “Overcoming Immune Suppression in the Tumor Microenvironment”
October 26, 2021 Ethics Conference Lara Cheslow & Ibram Mikhail "Emergency Use Authorizations: striking balance between speedy solution and safe practices"
October 19, 2021 Journal Club Ranju Kunwor “Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis”
October 12, 2021 Seminars in Human Investigation Margaret (Maggie) Gatti-Mays, MD, MPH, FACP  “Enhancing Immune Responses in Breast Cancer through Novel Therapeutic Combinations”
September 14, 2021 Ethics Conference Usman Baqai & Alisa Olmsted "Scientific reproducibility, transparency, and information sharing: to share or not to share?"
September 7, 2021 Seminars in Human Investigation Mark Yarchoan Targeting Neoantigens to Augment Antitumor Immunity for Hepatobiliary Malignancies
June 15, 2021 Journal Club Ida Micaily CRISPR-Cas9 Gene Editing in Sickle Cell Anemia
June 8, 2021 Seminars in Human Investigation Marco Davila, MD, PhD The Clinical Application of CD19-targeted CAR T Cells and Lessons Learned
May 25, 2021 Ethics Conference Alison O'Neill Consent, Assent, and Autonomy: Ethical Issues in Pediatric Research and Practice
May 18, 2021 Departmental Research Seminar Reena Ghosh Use of Ferumoxytol Enhanced Cardiac MRI in Patients with Congenital Heart Disease
April 27, 2021 Journal Club Alison O’Neill  Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600–Mutant Anaplastic Thyroid Cancer
April 13, 2021 Seminars in Human Investigation Kathryn Lurain MD,MPH, National Cancer Institute Cancer in People Living with HIV
March 25, 2021 Charles Gruber Lecturer and Grand Rounds (Special Seminar) Kathleen M. Giacomini, PhD, University of California, San Francisco Transporters in Pharmacology and Medicine:  Targets for Drug-Drug interactions, Drug-Nutrient Interactions and Genomic Medicine
March 23, 2021 Departmental Research Seminar Peter Altshular The Evolving Landscape of Heart Transplant: Optimizing Allograft Utility From Donor and Recipient
March 16, 2021 Journal Club Madion Crutcher  Personalized Identification of Optimal HIPEC Perfusion Protocol in Patient-Derived Tumor Organoid Platform
March 9, 2021 Seminars in Human Investigation Gary Peltz MD, PhD, Stanford University  Computational Genetic and AI-Enabled Translational Discovery
February 23, 2021 Ethics Conference Shaik Rashid Research in Prisons in the Post Covid-19 Era
February 16, 2021 Departmental Research Seminar Amanda McBride Overcoming resistance to BCL-2 inhibition in diffuse large B-cell lymphoma
February 9, 2021 Seminars in Human Investigation Sarah Holstein MD, PhD, University of Nebraska  Development of Geranylgeranyl Diphosphate Synthase Inhibitors for Multiple Myeloma
January 26, 2021 Ethics Conference Ranju Kunwor and Ida Micaily  Research Ethics in Public Health Emergencies
January 19, 2021 Departmental Research Seminar Ambika Chidambara Secondary analysis of a randomized controlled trial of intranasal corticosteroids in the treatment of mild to moderate pediatric obstructive sleep apnea
January 12, 2021 Seminars  in Human Investigation Prof. Ingolf Cascorbi, MD PhD FBPhS, Director, Institute of Experimental and Clinical Pharmacology Pharmacogenomics of ABC efflux transporters in TKI therapy
2020      
December 15, 2020 Journal Club Amanda McBride Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3 mimetic resistance in lymphomas
December 8, 2020 Ethics Conference Neil Zhao and Reena Ghosh  Retracted: A study of scientific integrity
December 1, 2020 Seminars  in Human Investigation Holly Ramage  Using Proteomics and Genomics to Unravel New Facets of Flaviviral Infection
November 24, 2020 Departmental Research Seminar Ranju Kunwor PARP inhibitor in Metastatic Breast cancer
November 17, 2020 Journal Club Shaik Rashid Graft composition as a predictor of outcomes in stem cell transplantation
November 10, 2020 Seminars  in Human Investigation Marc H. Scheetz Vancomycin Induced Kidney Injury.  Can Precision Dosing and Biomarkers Lessen the Insult?
October 27, 2020 Ethics Conference Madison Crutcher and Joshua Barton Hey, that's my DNA!: Genetic Testing and your privacy
October 20, 2020 Departmental Research Seminar John Flickinger Listeria-Based Vaccines Targeting Guanylyl Cyclase C (GCC) for Metastatic Colorectal Cancer
October 13, 2020 Seminars  in Human Investigation Young Hee Nam The role of epidemiology in drug drug interactions: warfarin and  sulfonylureas
September 22, 2020 Journal Club Ida Micialy Lurbinectidin as second-line treatment in small cell lung cancer
September 15, 2020 Ethics Conference Weelic Chong & Peter Altshuler Maintaining Ethical Standards in the Midst of a Pandemic
September 8, 2020 Seminars in Human Investigation Stephan Schmidt Creating Synergy: A Rising Tide Raises All Boats