Leadership
- Director, Division of Nephrology
- Robert L. Capizzi Professor in Medicine
Contact
211 S. Ninth Street
Suite 700
Philadelphia, PA 19107
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Bonita Falkner, MD
Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Publications
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
- What about Stage 1 Hypertension in Young Adults?
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth with Elevated Blood Pressure
- Primordial Prevention of High Blood Pressure in Childhood: An Opportunity Not to be Missed
- Association of blood pressure level with left ventricular mass in adolescents: SHIP AHOY
Maria P. Martinez Cantarin, MD
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, 10.1007/s40261-019-00764-x)
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Relationship of adipokines with insulin sensitivity in African Americans
- Relationship of blood pressure and obesity with inflammatory cytokines among African Americans
Pooja Singh, MD
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
- Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines
- The authors reply
Division Faculty Peer Reviewed Publications
- Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS
- Correction to: Opportunistic detection of type 2 diabetes using deep learning from frontal chest radiographs (Nature Communications, (2023), 14, 1, (4039), 10.1038/s41467-023-39631-x)
- Early outcomes of MR-guided SBRT for patients with recurrent pancreatic adenocarcinoma
- Association between elevated preoperative red cell distribution width and mortality after brain tumor craniotomy
- Sustained response to atogepant in episodic migraine: post hoc analyses of a 12-week randomized trial and a 52-week long-term safety trial
- A multi-institutional meningioma MRI dataset for automated multi-sequence image segmentation
- Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance)
- A rat-based preclinical platform facilitating transcatheter hepatic arterial infusion in immunodeficient rats with liver xenografts of patient-derived pancreatic ductal adenocarcinoma
- Accuracy of machine learning to predict the outcomes of shoulder arthroplasty: a systematic review
- Integrated transcriptomics and histopathology approach identifies a subset of rejected donor livers with potential suitability for transplantation
- Development and psychometric properties of appraisals of post traumatic spinal cord injury health scale in Iran
- XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53–p21 and p27 pathways
- Perspectives from patients with chronic lung disease on a telehealth-facilitated integrated palliative care model: a qualitative content analysis study
- Protection enhancement strategies of potential outbreaks during Hajj
- Mcl-1 mediates intrinsic resistance to RAF inhibitors in mutant BRAF papillary thyroid carcinoma
- GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults
- Occupational therapy students' perceptions of their experience in a role-emerging Level II fieldwork within higher education student services
- Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors
- PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress
- The nuclear import receptor Kapβ2 modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD