Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Division of Nephrology
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Publications
- Systolic Blood Pressure, Cardiovascular Health, and Neurocognition in Adolescents
- Cardiovascular Health Starts in the Womb
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
- What about Stage 1 Hypertension in Young Adults?
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth with Elevated Blood Pressure
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, 10.1007/s40261-019-00764-x)
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Relationship of adipokines with insulin sensitivity in African Americans
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Safety and Efficacy of Avacopan in Patients with Complement 3 Glomerulopathy: Randomized, Double-Blind Clinical Trial
- Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
Division Faculty Peer Reviewed Publications
- Chemoradiation treatment with or without concurrent tumor-treating fields (TTFields) therapy in newly diagnosed glioblastoma (GBM) patients in China
- Impact of chromatin on HIV-1 latency: a multi-dimensional perspective
- 5-hydroxymethylcytosine sequencing of plasma cell-free DNA identifies epigenomic features in prostate cancer patients receiving androgen deprivation therapies
- Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex
- Rideshare services for transportation assistance in gynecologic oncology: a quality improvement study
- Assessing the effects of long-COVID on mental health in the United States: a population based study
- Biologic Therapies for Discogenic Pain
- Self supervised artificial intelligence predicts poor outcome from primary cutaneous squamous cell carcinoma at diagnosis
- Accelerated symptom improvement in Parkinson’s disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial
- AXL signaling in cancer: from molecular insights to targeted therapies
- Genetic ancestry concordant RNA splicing in prostate cancer involves oncogenic genes and associates with recurrence
- Glucagon-like peptide-1 receptor agonists improve metabolic dysfunction-associated steatotic liver disease outcomes
- Surgical complication index for pediatric patients (SCIPP): A novel pediatric frailty index predicting postoperative complications in a study of 133 pediatric neurosurgical patients
- Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
- Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes
- Pulmonary pathology in culture-negative sepsis: a potential confounder for sepsis treatment and research
- ATM Expression and Activation in Ataxia Telangiectasia Patients with and without Class Switch Recombination Defects
- Evaluating Large Language Models for Automated CPT Code Prediction in Endovascular Neurosurgery
- Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
- The State of the Evidence for Medical Cannabis as a Treatment for Pain-related Sleep Impairments: Integrating Social Determinants of Health into Research Design and Policy