Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Division of Nephrology
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Publications
- Systolic Blood Pressure, Cardiovascular Health, and Neurocognition in Adolescents
- Cardiovascular Health Starts in the Womb
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
- What about Stage 1 Hypertension in Young Adults?
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth with Elevated Blood Pressure
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, 10.1007/s40261-019-00764-x)
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Relationship of adipokines with insulin sensitivity in African Americans
- Relationship of blood pressure and obesity with inflammatory cytokines among African Americans
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
- Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines
Division Faculty Peer Reviewed Publications
- Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
- The State of the Evidence for Medical Cannabis as a Treatment for Pain-related Sleep Impairments: Integrating Social Determinants of Health into Research Design and Policy
- Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma
- NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats
- In the era of transition from fiction to reality: Robotic-assisted neurointervention-a systematic review and meta-analysis
- Risk of estrogen-driven malignancies in females on 5-alpha reductase inhibitors
- Rates of sepsis among patients hospitalized for hidradenitis suppurativa
- Cancer Trends in Inborn Errors of Immunity: A Systematic Review and Meta-Analysis
- Developmental lead exposure and aggression in male rats: Influences of maternal care and environmental enrichment
- Skeletal and dental tissue mineralization: The potential role of the endoplasmic reticulum/Golgi complex and the endolysosomal and autophagic transport systems
- Outcome measures in rodent models for spinal cord injury and their human correlates
- Knowledge and Attitudes About Perinatal Marijuana Use Among US Postpartum Mothers: A Better Outcomes Through Research for Newborns Network Study
- Characteristics and outcomes of cardiac amyloid disease after heart transplantation: A systematic review and meta-analysis
- Use of mean apparent propagator (MAP) MRI in patients with acute ischemic stroke: A comparative study with DTI and NODDI
- Computational urban design: A simulation and data-driven approach to designing a sustainable built environment
- A radically transformative student-centered approach to the design of net-zero buildings
- The use of precision radiotherapy for the management of cancer-related pain in the abdomen
- Antiseizure medications and their differing effects on cardiovascular risk
- An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors
- Superotemporal predisposition to traumatic subretinal fibrosis in Stargardt disease: A case report