The Interventional Radiology Division is involved in a variety of research endeavors. Members of the division have recently participated in federally funded trials, including:

Grant-funded prospective trials

1. Evaluating Uterine Fibroid Embolization with Contrast-Enhanced Ultrasound Imaging (CEUS) and Superb Microvascular Imaging (SMI)
2. BCNU (300mg) chemoembolization for the treatment uveal melanoma hepatic metastases
3. A Phase II randomized double-blinded clinical study comparing treatment of uveal melanoma liver metastases with granulocyte macrophage-colony stimulating factor (GM-CSF) versus bland embolization
4. A phase I/IIa NIH supported clinical single-institutional trial.  Immunoembolization of malignant liver tumor with granulocyte macrophage-colony stimulating factor (GM-CSF) and ethiodized oil followed by gelatin sponge pledgets
5. Ultrasound Microbubble Destruction and Perfusion Quantification for Improving Radioembolization Therapy of Hepatocellular Carcinoma

Single-institutional trials

1. A Single-Institutional Study using Immunoembolization (GM-CSF) and Systemic Ipilimumab and Nivolumab in Patients with Uveal Melanoma Metastatic to the Liver
2. Pilot study of Yttrium-90 Microspheres (SIR-Spheres) Therapy for the Treatment of Uveal Melanoma Liver Metastases.  Phase II, Single Institution, Clinical Trial
3. Circulating Tumor DNA in High-Risk Primary and Recurrent Uveal Melanoma Patients

Multi-institutional trials

1. Survey of Co-Morbidities of Pelvic Congestion Syndrome Pre and Post Treatment
2. A Feasibility Multicenter Study of Sequential Hepatic Internal Radiation and Systemic Ipilimumab and Nivolumab in Patients with Uveal Melanoma Metastatic to Liver
3. Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer (STOP-HCC)
4. A Multicenter Observational Registry to Develop Ablation Parameter Guidance for Microwave Liver Ablation of Soft Tissue Lesions (NOLA) NEUwave
5. Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial) (C-TRACT)
6. A Randomized, Controlled, Phase 3 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment in Patients with Hepatic-Dominant Ocular Melanoma Metastases
7. A Multicenter Trial using LC Bead Embolization Agent with Doxorubicin; Chemoembolic Agent for use in the Treatment of Uveal Melanoma Liver Metastases