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Division of Pulmonary, Allergy & Critical Care

Pulmonary, Allergy & Critical Care Medicine Clinical Home

Leadership

Jesse Roman, MD
  • Ludwig A. Kind Professor in Medicine
  • Division Director, Pulmonary & Critical Care Medicine
  • CEO, Jane & Leonard Korman Respiratory Institute
Department of Medicine

Contact

Division of Pulmonary, Allergy & Critical Care Medicine

843 Walnut Street
Suite 650
Philadelphia, PA 19107

SKMC Alumni
Support Department of Medicine

Research Activities

The research arm of the Division of Pulmonary, Allergy & Critical Care is the Jane and Leonard Korman Lung Center at Jefferson. The focus includes lung cancer as well as benign diseases, such as asthma, sarcoidosis and pulmonary fibrosis, with special emphasis on lung biology.

Several key entities will interact closely and collaboratively to advance our understanding of lung disease and provide a platform for education of our trainees and improve patient care:

Scholarship and research covers a broad spectrum, including:

  • Sponsored clinical trials (typically multi-center pharma trials with strict study design with random allocation)
  • Quality assurance initiatives geared to monitoring, education and improving compliance of accepted practice
  • Investigator-initiated data collection of a particular disease cohort or intervention
  • Establishing registries for data or biobanks for future studies
  • Correlative or translational studies involving human specimens to gain proof-of-concept insights into disease mechanisms
  • Formal controlled laboratory models with experimental design involving mouse models, in-vitro studies, etc.

All of these activities are currently occurring in the Pulmonary, Allergy & Critical Care Division at Thomas Jefferson University and Thomas Jefferson University Hospitals.  Clinicians, clinical scientists and laboratory scientists are equally engaged and valued. This represents an outstanding environment for growth of a fellow-in-training or academic faculty.

Clinical Trials & Projects

Clinical research is considered to be vital for the mission of an academic division and typically faculty gravitate to academic centers to participate in scholarship, discovery and innovation. A healthy training environment which includes knowledge creation is an integral part of Pulmonary, Allergy & Critical Care Medicine Fellowship training as mandated by the Accreditation Committee on Graduate Medical Education and the division. Participation in an active research program is an essential component for fellows enrolled in subspecialty fellowship training programs. As such, our program provides an opportunity for fellows to participate in research and other scholarly activities. The program strives to ensure a meaningful, supervised research experience with appropriate protected time. Fellows learn the standards of ethical conduct of research, design and interpretation of research studies, responsible use of informed consent, research methodology, methods of choosing and performing statistical analysis, and interpretation of data.

The division’s scholarly activities are complemented by support and expertise from:

  1. Jefferson Coordinating Center for Clinical Research (JCCCR)
  2. Center for Translational Medicine (CTM)
  3. Graduate Studies Programs

Sponsor: F. Hoffmann-La Roche Ltd

Purpose: A phase III study to assess the safety and efficacy of the investigational drug, PRM151 vs. placebo, given IV over a period of 52 weeks to subjects with a diagnosis of idiopathic pulmonary fibrosis (IPF). 2020-present

Sponsor: F. Hoffmann-La Roche Ltd

Purpose: Clinical trial evaluating the long-term safety, efficacy and pharmacokinetics of open-label PRM-151 in patients with idiopathic pulmonary fibrosis (IPF). 2021-present

Sponsor: Novartis Institutes for Biomedical Research

Purpose A subject and Investigator Blinded, Randomized, Placebo-Controlled, Repeat-dose, Multicenter study to investigate Efficacy, Safety, and Tolerability of CMK389 in Patients with Chronic Pulmonary Sarcoidosis. 2021-present

Sponsor: Bellerophon Pulse Technologies LLC (Pulse-PHPF-001)

Purpose: A randomized, Double-Blind, Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed, Inhaled Nitric Oxide (iNo) in Subjects at Risk of Pulmonary Hypertension Associated with Pulmonary Fibrosis on Long Term Oxygen Therapy (Part1 and part2). 2020-present

Sponsor: Boehringer Ingelheim

Purpose: IPF-PRO/ILD-PRO Registry, Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype Prospective Outcomes (ILD-PRO). 2020-present

Sponsor: AstraZeneca Pharmaceuticals LP (Chronicle)

Purpose: Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States. 2020-present

Sponsor: AstraZeneca Pharmaceuticals LP (LOGOS)

Purpose: A Randomized, Double-Blind, Double Dummy, Parallel Group, Multicenter 24 to 52 Week Variable Length Study to Assess the Efficacy and Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler (MDI) Relative to Budesonide and Formoterol Fumarate MDI and Symbiont® Pressurized MDI in Adult and Adolescent Participants with Inadequately Controlled Asthma (LOGOS). 2021- present

Sponsor: Veracyte

Purpose: An observational study of the clinical utility of Envisia Genomic Classifier. 2021- present

Sponsor: Horizon Therapeutics Ireland DAC

Purpose: Randomized, Doubleblind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN 825 in Subjects with Idiopathic Pulmonary Fibrois

Sponsor: ContraFect Corporation

Purpose: A Randomized, Doubleblind, Placebo-controlled, Multi-site, Phase III Study to Evaluate the Safety and Efficacy of CD24Fc in COVID-19 Treatment. 2020-present

Sponsor: Karyopharm Therapeutics, Inc

Purpose: a phase 2 randomized single-blind study to evaluate the activity and safety of low dose oral selinexor (KPT-330) in patients with severe COVID-19 infection. 2020-present

Sponsor: FibroGen, Inc.

Purpose: Open-Label, Randomized, Parallel-Arm, Phase 2 Study of the Efficacy and Safety of Intravenous Pamrevlumab, a Monoclonal Antibody Against Connective Tissue Growth Factor (CTGF), in Hospitalized Patients with COVID-19 Disease Due to SARS-COV-2 Infection. 2020-present

Sponsor: Incyte Corporation

Purpose: A phase 3, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of Ruxolitinib in participants with COVID-10- Associated ARDS who require Mechanical Ventilation. 2020-present

Sponsor: Janssen Research and Development, LLC

Purpose: Prospective, multi-center, double-blind, randomized, active-controlled, triple-dummy, parallel-group, group-sequential, adaptive Phase 3 clinical study to compare the efficacy and safety of Macitentan and tadalafil monotherapies with the corresponding fixed dose combination in subjects with pulmonary arterial hypertension (PAH), followed by an open-label treatment period with Macitentan and tadalafil fixed dose combination therapy. 2020-present

Sponsor: Genentech, Inc.

Purpose: Long-Term, Follow-Up,Study of Patients with COVID-19Associated Pneumonia Who

Participated in a Designated Genentech/Roche Sponsored Study or Genentech/Roche Supported Investigator-Initiated Placebo-Controlled or Active-Controlled Study. 2020-present

Sponsor: Delfi Diagnostics, Inc.

Purpose: CASCADE-LUNG: Cancer Screening Assay using DELFI; A Clinical Validation Study in Lung. 2021-present

Grant: NIH through the University of Alabama

Purpose: Study of Therapeutic Plasma Exchange, Rituximab, and Intravenous Immunoglobulin for Acute Exacerbations of Idiopathic Pulmonary Fibrosis. 2020-present

Grant: Cystic Fibrosis Foundation

Purpose: Participation in the Cystic Fibrosis Patient Registry. 2020-present

Grant: Foundation for Sarcoidosis Research

Lung Tissue Remodeling in Sarcoidosis: Relationship to Clinical Phenotype and Disease Severity and Progression (TRAPS Trial). 2020-present

Grant; Indiana University

Purpose: HomE Reported Outcomes in People with CF Taking Trikafta(Hero)

Under Construction

2020 to Present

Saqib Baig, MD
  • Baig SH, Gorth DJ, Yoo EJ. Critical Care Utilization and Outcomes of Interhospital Medical Transfers at Lower Risk of Death. Journal of Intensive Care Medicine. June 2021.
  • Haribhakti N, Agarwal P, Vida J, Panahon P, Rizwan F, Orfanos S, Stoll J, Baig S, Cabrera J, Kostis JB, Ananth CV, Kostis WJ, Scardella AT. A Simple Scoring Tool to Predict Medical Intensive Care Unit Readmissions Based on Both Patient and Process Factors. J Gen Intern Med. 2021 Apr;36(4):901-907. doi: 10.1007/s11606-020-06572-w. Epub 2021 Jan 22. PMID: 33483824; PMCID: PMC8041987.
Michael Baram, MD
  • Kathleen Biblowitz, MD, Megan Mullin, CRNP, Lydia McDermott PAC, Alyssa Sykuta, PharmD, Michael Baram, MD; Hitoshi Hirose, MD, PH D. A multidisciplinary approach to prolonged extracorporeal membrane oxygenation for acute respiratory distress syndrome due to coronavirus 2019- case report. AME. Submitted Manuscript ID: ACR-21-51
  • Blazoski, CM, Baram, M, Yang, Q, Hirose, H. Outcomes of extracorporeal membrane oxygenation in influenza versus COVID-19 during the first wave of COVID-19. J Card Surg. Aug 2021; 1- 7.  PMID:  34369601
  • Sang Hoon Woo, Arturo J. Rios-Diaz, Alan A. Kubey,  Dianna R. Cheney-Peters, Lily L. Ackermann, Divya M. Chalikonda, Chantel M Venkataraman, Joshua M. Riley, Michael Baram. Development and Validation of a Web-Based Severe COVID-19 Risk Prediction Model. The American Journal of the Medical Sciences. Accepted April 2021.  Manuscript   MAJ 20-2248R1
  • Cameron Blazoski, Michael Baram, Hitoshi Hirose. Outcomes of Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome due to COVID-19, lessons learned from the first wave of COVID 19. Journal of Cardiac Surgery. March 19, 2021  DOI: 10.1111/jocs.15512   PMID: 33738855       
  • Michelle Schafer, Michael Baram, and Gregory Kane. Understanding Dead Space in Giraffes, and its Application to Critically Ill COVID-19 Patients. Submitted Respirations.
  • Dagan Coppock; Michael Baram; Anna Marie Chang; Patricia Henwood; Alan Kubey; Ross Summer; John Zurlo; Michael Li; Bryan Hess   COVID-19 Treatment Combinations and Associations with Mortality in a Large Multi-Site Healthcare System. PLOS- One.  June 11, 2021    https://doi.org/10.1371/journal.pone.0252591 
  • Haritha Reddy, Abhiraj Saxena, Melissa Austin, Elizabeth J Maynes, Thomas J O'Malley, Mark Gadda, Nawar Al-Rawas, Michael Baram, Bharat K Awsare, Howard Todd Massey, Vakhtang Tchantchaleishvili.  Utilization of Extracorporeal Life Support for Diffuse Alveolar Damage: A Systematic Review. Artificial Organs. 2021; 00:1–10. https://doi.org/10.1111/aor.13861
  • Li M, Yoo EJ, Baram M, McArthur M, Skeehan C, Awsare B, George G, Summer R, Zurlo J, Jallo J, Roman J. Tocilizumab in the Management of COVID-19: A Preliminary Report. Am J Med Sci. 2020 Nov 9:S0002-9629(20)30491-2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649658/ PMID: 33358502; PMCID: PMC7649658.
  • Au C, Gupta E, Khaing P , DiBello J, Chengsupanimit T, Mitchell E, West FM, Baram M, Awsare B, Kane GC. Clinical presentations and outcomes in pulmonary embolism patients with cancer. J Thromb Thrombolysis. 2020 Oct 12.
  • Gupta E, Awsare B, Hiroshi H, Cavarocchi N, Baram M. Don't Drive Blind: Driving Pressure to Optimize Ventilator Management in ECMO. Lung. 2020;198(5):785-792. doi:10.1007/s00408-020-00381-y. PMID: 32705400
  • Michael Baram, Bharat Awsare, Geno Merli. Intensive Care Units as a Place to Manage Pulmonary Emboli. Critical Care Clinics. July 2020. Vol 36, Issue 3,  pages  xiii-xiv. PMID: 32473701 https://doi.org/10.1016/j.ccc.2020.04.001
  • Michael Baram, Bharat Awsare, Geno Merli. Pulmonary Embolism in Intensive Care Unit. Critical Care Clinics. July 2020. Vol 36, Issue 3. Pages 427-435. PMID: 32473689 
  • Judah Brown, Andrew Moyer, Michael Baram and Cara McDaniel.  Impact of Vasopressor Initiation and Discontinuation Sequence on Mortality in Septic Shock: A Retrospective Review.  Surgical Case Reports 3(2): 2-7. Feb 2020. DOI: 10.31487/j.SCR.2020.01.05  
  • Gupta, E., Carey, K., McDermott, L., Cavarocchi, N., Hirose, H. and Baram, M. (2020) Role of Serum Cytokine Levels in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation Support. World Journal of Cardiovascular Surgery, 10, 1-10.  DOI: 10.4236/wjcs.2020.101001              

Non peer reviewed

Julie Barta, MD
  • Barta JA, Shusted CS, Ruane B, Pimpinelli M, McIntire RK, Zeigler-Johnson C, Myers RE, Evans NR, Kane GC, Juon HS. Racial Differences in Lung Cancer Screening Beliefs and Screening Adherence. Clinical Lung Cancer 2021; accepted, in press.
  • Shusted CS, Evans NR, Juon HS, Kane GC, Barta JA. Association of Race with Lung Cancer Risk Among Adults Undergoing Lung Cancer Screening. JAMA Network Open 2021; 4(4):e214509. PMID: 33822072.
  • Juon HS, Hong A, Pimpinelli M, Rojulpote M, McIntire R, Barta JA. Racial Disparities in Occupational Risks and Lung Cancer Incidence: Analysis of the National Lung Screening Trial. Prev Med 2021; 143: 106355. PMID: 33301822.
  • Lake, M, Shusted CS, Juon H, McIntire RK, Zeigler-Johnson C, Evans NR, Kane GC, Barta JA. Black Patients Referred to a Lung Cancer Screening Program Experience Lower Rates of Screening and Longer Time to Follow-Up. BMC Cancer 2020; 20(1):561. PMID:32546140.
Christina Chien, MD
  • Block P, Barnes A, Chien C, Tholey D, Hess B, DeSimone J, Civan J. Clinical outcomes for nosocomial versus community-acquired spontaneous bacterial peritonitis. Digestive Disease Week National Conference. May 2021.
  • Swaminathan A, Chien C, Emlet L. A 47-year-old woman with shortness of breath. In:Weinstock MB, ed. Bouncebacks! Critical Care. Columbus, OH: Anadem Publishing; 2021.
Megan Ford, MD
  • Clark, M.M., Nayak, A.P., Cohn, J.R., Morelli, H., Ford, M.K. Species specific evaluation of 2 patients with suspected crab allergy. J Allergy Clin Immunol Pract. 2021 Jan: 9(1); 511-513
Gautam George, MD
  • Li M, Yoo EJ, Baram M, McArthur M, Skeehan C, Awsare B, George G, Summer R, Zurlo J, Jallo J, Roman J. Tocilizumab in the Management of COVID-19: A Preliminary Report. Am J Med Sci. 2021 Feb;361(2):208-215. doi: 10.1016/j.amjms.2020.11.005. Epub 2020 Nov 9. PMID: 33358502;
  • Gulati A, Pomeranz C, Qamar Z, Thomas S, Frisch D, George G, Summer R, DeSimone J, Sundaram B. A Comprehensive Review of Manifestations of Novel Coronaviruses in the Context of Deadly COVID-19 Global Pandemic. Am J Med Sci. 2020 Jul;360(1):5-34. doi: 10.1016/j.amjms.2020.05.006. Epub 2020 May 11.
  • Kabadi RA, Shah M, Marhefka GD, George G, Awsare B, Terai M, Sato T. Rapid, Fatal Acute Right Ventricular Failure After Locoregional Cytokine Therapy for Uveal Melanoma Liver Metastases. Tex Heart Inst J. 2020 Jun 1;47(3):224-228. doi: 10.14503/THIJ-18-6762.
  • Hilton R, Summer R, Roman J, Sundaram B, George G. E-cigarettes and Vaping Associated Lung Injury: A Case Series and Brief Review. Am J Med Sci. 2020 Mar;359(3):137-139. doi: 10.1016/j.amjms.2020.01.003. Epub 2020 Jan 13. PMID: 32089155.
Monica Gupta, MD
  • Phillips, E.C., Gupta, M., Li, RC., Sohn, J.K., Lawrence, M.G. “Novel Pathogenic C2 Variant Associated with Disseminated GBS Infection.” J Clin Immunol. 2020 May 8.
Robert Hilton, MD
  • Hilton R, Summer R, Roman J, Sundaram B, George G. E-cigarettes and Vaping Associated Lung Injury: A Case Series and Brief Review. The American Journal of the Medical Sciences, March 2020, 359(3): 137–139.
Prarthna Kulandaisamy, MD
  • Gold,E.,Gandler,A., Kulandaisamy,P.C.,2020 Rare gastrobronchial fistula mistaken for aspiration pneumonia in a patient with esophageal cancer:A case report.DOI:https://doi.org?10.1016/j.chest 2020.8
Salvatore Mangione, MD  
  • Mangione S. The AJMS in the Beginning - Nathaniel Chapman, William Osler, and the Philadelphia Story. Am J Med Sci. 2020 Feb;359(2):59-60.
  • Mangione S. When Disease Strikes the Leader: What Should We Know? J Gen Intern Med. 2020 Oct;35(10):3053-3056. doi: 10.1007/s11606-020-06060-1. Epub 2020 Jul 27. PMID: 32720241; PMCID: PMC7573095.
  • Mangione S., Mockler GL. In Search of Hemingway’s Great War. Pharos Alpha Omega Alpha Honor Med Soc. Autumn 2020: 14-19.  https://alphaomegaalpha.org/pharos/2020/Autumn/2020_Autumn_Mangione.pdf
  • Mangione S, Post SG. The Moral lesson of Covid-19: A call for renewal. Am J Med Sci. 2021 Feb;361(2):146-150. doi: 10.1016/j.amjms.2020.11.018. Epub 2020 Nov 23. PMID: 33349440.
  • Mangione S, Borghi L, Bianucci R. Mazzini at 150: the Italian death of a London exile. Intern Emerg Med. 2021 Apr 7. doi: 10.1007/s11739-021-02728-6. Epub ahead of print. PMID: 33826075.
  • Mangione S. The observation of art and the art of observing individuals with physical differences. Am J Med Genet C Semin Med Genet. 2021 Jun;187(2):134-140. doi: 10.1002/ajmg.c.31898. Epub 2021 May 13. PMID: 33982435.
  • Mangione S, Tykocinski ML. Virchow at 200 and Lown at 100 - Physicians as Activists. N Engl J Med. 2021 Jul 22;385(4):291-293. doi: 10.1056/NEJMp2103050. Epub 2021 Jul 17. PMID: 34279066.
  • Mangione S, Mandell BF, Post SG. The Language Game: We Are Physicians, Not Providers. Am J Med. 2021 Jul 20. ISSN 0002-9343, https://doi.org/10.1016/j.amjmed.2021.06.031. (https://www.sciencedirect.com/science/article/pii/S0002934321004423)
Christopher McGrath, MD
  • McDonough G, Khaing P, McGrath C, Yoo E, et al. “The Use of High-Flow Nasal Oxygen in the ICU as a First-Line Therapy for Acute Hypoxemic Respiratory Failure Secondary to Coronavirus Disease 2019.” Critical Care Explorations, Oct 2020.
Jessica Most, MD
  • D'Souza G, Nwagu U, Ghanti R, Estephan L, Barton B, Unsal AR, Rabinowitz M, Rosen M, Nyquist G, Cohn J, Most JF, Toskala E. Outcomes of aspirin exacerbated respiratory disease patients treated with aspirin desensitization and biologics. International Forum of Allergy and Rhinology. In production.
  • Most JF, Ambrose C, Chung Y, Kreindler J, Near A, Brunton S, Cao Y, Huang H, Zhao X. Real-World Assessment of Asthma Specialist Visits among US Patients with Severe Asthma. JACI In Practice. 2021;Oct;9(10):3662-3671.e1. Epub June 2021.
  • Yoo E, Most JF, Lee N, McWilliam T, Plante L, Schulman E. Improving asthma symptoms among inner-city women during pregnancy: a prospective cohort intervention. JACI In Practice.   2021;Oct;9(10):3672-3678. Epub May 2021.
  • Most JF, Bork S. New Developments in Asthma Therapeutics. Current Opinion in Pharmacology 2020, 51:59-65.
  • Chitguppi C, Patel P, Gandler A, Murphy K, Khoury T, Monostra P, Bork S, Toskala E, Rabinowitz M, Rosen M, Nyquist G, Most, JF. Effect of Benralizumab in patients with Severe Eosinophilic asthma and Chronic Rhinosinusitis with nasal polyps : A case series." American Journal of Rhinology & Allergy; 2021; Sep;35(5):559-567.  Epub December 2020.
  • Leung S, Lee P, Most JF, Sundaram B. Images in COPD: Idiopathic Emphysema in a Never Smoker. Chronic Obstr Pulm Dis. 2020; 7(2): 130-133
David Oxman, MD
  • Oxman DA. Less Lumping and More Splitting: Why We Should Not Call COVID Sepsis. Crit Care Med. 2021 Jun 1;49(6):e656-e657. PMID: 34011839.
  • Oxman D, Guttman O, Brooks S, Kairys J, Riggio J. Using the Electronic Health Record for Crisis Allocation: Proceed With Caution. Am J Med Qual. 2021 Apr 2. PMID: 33828050.
  • Hughes K, Hussaini Z, Shah MK, Hilton R, Oxman D. COVID-19 and Acute Pulmonary Embolism: A Case Series and Brief Review. Am J Med Sci. 2021 May; 361(5):646-649. Epub 2021 Feb 10. PMID: 33773760.
  • Oxman D. The Crisis in Crisis Standards of Care. Ann Am Thorac Soc. 2021 Feb 5. Epub ahead of print. PMID: 33544065.
  • Oxman D, Marks J, Yoo E, Goldman R. Comment on "Tracheotomy in Ventilated Patients with COVID-19". Ann Surg. 2020 Nov 17. Epub ahead of print. PMID: 33214423.
  • Oxman D, Lohr K, Gupta E, Madara J, Len E, Hseih J. Incidence of Multidrug Resistant Infections in Emergency Department Patients with Suspected Sepsis. Am J Med Sci. 2020 Dec;360(6):650-655.. Epub 2020 Jul 16. PMID: 32868035.
  • Beal ML, Oxman DA, Becker MA. Non-urgent Surgical Intervention Over Objection in a Patient Who Lacks Capacity: A Case Report. Psychosomatics. 2020 May-Jun;61(3):277-280.. Epub 2019 Jul 24. PMID: 31466812.

Non peer reviewed

  • Fischkoff K, Derrington S, Helth C, Oxman D, Shepherd L, “ Donation After Circulatory Death with Normothermic Regional Perfusion: A Brief Ethical Analysis Society of Critical Care Medicine Critical Connections, Spring 2021.
  • Oxman D, “Health Care Workers Need to Lead on COVID-19 Vaccination.” Bioethics Net Blog. December 21, 2020.
  • Oxman D, “Considering Preexisting Conditions in a Crisis Like Coronavirus is Not Discrimination,” Philadelphia Inquirer, April 16, 2020.
Jesse Roman, MD
  • Greenwell J, Torres-Gonzalez E, Ritzenthaler JD, Watson W, Roman J.  Impact of sex, age and diet on the cysteine/cystine and glutathione/glutathione disulfide plasma redox couples in mice.  J Nutritional Biochemistry, 84:108431, 2020.  doi: 10.1016/j.jnutbio.2020.108431.
  • Gualdoni J, Ritzenthaler J, Burlen J, Stocker A, Abell T, Roman J, Nunley DR.  Gastrointestinal reflux and microaspiration in lung transplant recipients: the utility of a single esophageal manometry and pH probe monitoring study.  Transplant Proc  52: 977-981, 2020
  • Zheng Y, Merchant ML, Burke T, Ritzenthaler JD, Gaweda A, Roman J, Watson WH, Li M, Benz F.  Redox states of protein cysteines in pathways of protein turnover and cytoskeleton dynamics are changed with aging and reversed by Slc7a11 restoration in mouse lung fibroblasts. Oxidative Med & Cellul Longevity   2020 Jun 7;2020:2468986. doi: 10.1155/2020/2468986.
  • Flamenbaum M, Roman J.  Endemic and emerging coronavirus pulmonary infections.  Am J Med Sci.  2020 Jun 12:S0002-9629(20)30255-X. doi: 10.1016/j.amjms.2020.06.013.
  • Greenwell JC, Torres-Gonzalez E, Ritzenthaler JD, Roman J.  Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression.  Cancer Biology & Therapy.  In press.
  • Todd JL, Neely ML, Overton R, Mulder H, Roman J, Lasky JA, de Andrade JA, Huang H, Leonard TB, Hesslinger C, Noth I, Belperio J, Flaherty KR, Palmer SM.  Association nof circulating proteins with death or lung transplantation in patients with idiopathic pulmonary fibrosis in the IPF-PRO Registry cohort.  Lung.  Submitted.
Michael Stephen, MD
  • O’Hayer, CV, O’Loughlin CM, Nurse CN, Smith PJ, Stephen M. ACT with CF: A telehealth and in person feasibility study to address anxiety and depressive symptoms among people with cystic fibrosis. Journal of Cystic Fibrosis 2020; December.
  • Stephen M, Fiel S, Zanni R, Hadjiliadis D. Prevalence of Medical Marijuana Use in Cystic Fibrosis. BMC Complementary Medicine 2020;323.
  • Woytanowski JR, Ko W, Granche J, Stephen M. Outcomes of Septic Patients Requiring Renal Replacement Therapy. Journal of the Intensive Care Society, April 2020
  • Abramian O, Singhal S, Stephen M. A 49-year-Old Man with cough and hand, wrist and knee pain. Chest, February 2020.
Ross Summer, MD
  • Hoora Shaghaghi, Rachel Para, Cara Tran, Jesse Roman, Yemaiza Ojeda-Lassalle, Freddy Romero, Ross Summer Glutamine restores mitochondrial respiration in bleomycin-injured epithelial cells under review
  • Metra B, Summer R, Brooks SE, George G, Sundaram B. Racial disparities in COVID-19 associated pulmonary embolism: A multicenter cohort study. Thromb Res. 2021 S [34274560].
  • Shaghaghi, H., Karina, Cuevas-Mora, Para, R., Tran, C. Roque, W., Robertson, M., Rosas, I., Summer, R., Romero, F. Aging cell  2021 Jul 8;13(13):16922-16937*co-senior author [34238764]
  • Coppock, D., Baram, M., Chang, AM, Henwood, P., Kubey, A., Summer, R., Zurlo, J., Li, M., Hess, B., COVID-19 Treatment Combinations and Associations with Mortality in a Large Multi-Site Healthcare System, Plos One Medicine.
  • Li M, Yoo EJ, Baram M, McArthur M, Skeehan C, Awsare B, George G, Summer R, Zurlo J, Jallo J, Roman Tocilizumab in the Management of COVID-19: A Preliminary Report. J.Am J Med Sci. 2021 [PMID: 33358502]
  • Cuevas-Mora K, Roque W, Shaghaghi H, Gochuico BR, Rosas IO, Summer R, Romero F. Hermansky-Pudlak syndrome-2 alters mitochondrial homeostasis in the alveolar epithelium of the lung. Respir Res. 2021 Feb 8;22(1):49 [PMID: 33557836] * co-senior author
  • Schultz, CW, Dhir, T., McCarthy, GA., Nevler, A., McCoy, M., Jiang W., Brown SZ,  Goetz, A., Calvert V., Vishwakarma., V., Vang D., Dang H., Cassel J., Summer R., Shaghaghi., H., Pommier Y., Baechler A., Yeo., C. Petricoin EF., Salvino J, Singh PJ., Dixon DA, Brody, JR. Repurposing an FDA approved anthelmintic therapy to halt the growth of pancreatic cancer. Mol Cancer Ther. 2021 Aug 19 [34413127]

Non peer reviewed

  • Kramer, D., Summer, R. Airway Hydration in Sjögren’s Pulmonary Disease The Role of Nebulized Saline Solution Beyond Xerotrachea: Accepted
  • Gulati A, Pomeranz C, Qamar Z, Thomas S, Frisch D, George G, Summer R, DeSimone J, Sundaram B. A Comprehensive Review of Manifestations of Novel Coronaviruses in the Context of Deadly COVID-19 Global Pandemic. Am J Med Sci. 2020 Jul;360(1):5-34
  • Perez R, Summer R. On Race and the Environment in the COVID-19 Pandemic.Am J Med Sci. 2020 Oct;360(4):327-328
  • Fonseca M, Summer R, Roman Acute Exacerbation of Interstitial Lung Disease as a Sequela of COVID-19 Pneumonia. J.Am J Med Sci. 2021
  • Summer AK, Summer R, Solga SF, Spacek LA. COVID-19 Retesting in the Primary Care Setting. Am J Med Sci. 2020 May
  • Hilton, R., Summer, R., Roman, J., Sundaram, B., George, G. E-cigarettes and vaping associated lung injury: a case series and brief review. Am J Med Sci. 2020.
Urvashi Vaid, MD, MS
  • Ziring D, Berg K, Mingioni N, Papanagnou D, Vaid U, Herrine S. 2020 AAMC Snapshots in Medical Education in the United States and Canada Sidney Kimmel Medical College at Thomas Jefferson University. Acad Med. 2020;95: S444–S448.
Frances West, MD
  • Khaing P, Paruchuri A, Eisenbrey JR, Merli GJ, Gonsalves CF, West FM, Awsare BK. First year experience of a pulmonary embolism response team with comparisons of outcomes between catheter directed therapy versus standard anticoagulation. Hosp Pract (1995). 2020 Feb;48(1):23-28. doi: 10.1080/21548331.2020.1706315. Epub 2020 Jan 3. PMID: 31847615
  • Choi JH, O'Malley TJ, Maynes EJ, Weber MP, D'Antonio ND, Mellado M, West FM, Galanis T, Gonsalves CF, Marhefka GD, Awsare BK, Merli GJ, Tchantchaleishvili V. Surgical Pulmonary Embolectomy Outcomes for Acute Pulmonary Embolism. Ann Thorac Surg. 2020 Mar 6:S0003-4975(20)30345-3. doi: 10.1016/j.athoracsur.2020.01.075. PMID: 32151576
  • Root CW, Mitchell OJL, Brown R, Evers CB, Boyle J, Griffin C, West FM, Gomm E, Miles E, McGuire B, Swaminathan A, St. George J, Horowitz JM, DuCanto J. Suction Assisted Laryngoscopy and Airway Decontamination (SALAD): A Technique for Improved Emergency Airway Management., Resuscitation Plus, 2020 Mar-Jun;1-2. 
  • Marbach JA, Almufleh A, Di Santo P, Simard T, Jung R, Diemer G, West FM, Millington SJ, Mathew R, Le May MR, Hibbert B. A Shifting Paradigm: The Role of Focused Cardiac Ultrasound in Bedside Patient Assessment. Chest. 2020 Nov;158(5):2107-2118. doi: 10.1016/j.chest.2020.07.021. Epub 2020 Jul 21. PMID: 32707179.
  • West FM, Saati A, Lewiss RE. A brief history of point-of-care transesophageal echocardiography in the USA. Eur J Emerg Med. 2020 Oct 16. doi: 10.1097/MEJ.0000000000000767. Epub ahead of print. PMID: 33079739.
  • Au C, Gupta E, Khaing P, Dibello J, Chengsupanimit T, Mitchell EP, West FM, Baram M, Awsare BK, Kane GC. Clinical presentations and outcomes in pulmonary embolism patients with cancer. J Thromb Thrombolysis. 2021 Feb;51(2):430-436. doi: 10.1007/s11239-020-02298-y. Epub 2020 Oct 12.
  • Mitchell OJL, Yuriditsky E, Johnson NJ, Doran O, Buckler DG, Neefe S, Seethala RR, Motov S, Moskowitz A, Lee J, Griffin KM, Shashaty MGS, Horowitz JM, Abella BS; West FM. Coronavirus 2019 In-Hospital Cardiac Arrest (COVID IHCA) Study Group. In-hospital cardiac arrest in patients with coronavirus 2019. Resuscitation. 2021 Mar;160:72-78. doi: 10.1016/j.resuscitation.2021.01.012. Epub 2021 Jan 27. PMID: 33515638
Erika Yoo, MD
  • Ahmad D, Yoo EJ. Asthma in pregnancy. In: Lapinsky SE, Plante LA, eds. Respiratory Disease in Pregnancy. Cambridge, UK; New York, NY: Cambridge University Press, 2020.
  • Oxman D, Marks J, Yoo E, Goldman R. Comment on "Tracheotomy in Ventilated Patients with COVID-19.” Ann Surg. 2020 Nov 17. PMID 33214423.

Publications

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